DHA Found to Shrink Tumors, Aid Use of Chemotherapy Drug

DHA, an omega-3 fatty acid found in fish oils, has been shown to
reduce the size of tumors and enhance the positive effects of the
chemotherapy drug cisplatin, while limiting its harmful side effects.
These experiments, described in the journal "Cell Division," provide
some support for the many health benefits often suggested for omega-3
acids.

Professor A. M. El-Mowafy and his team from Mansoura University
(Egypt) studied DHA’s effects on solid tumors growing in mice, and
investigated how this fatty acid interacts with cisplatin, a
chemotherapy drug that is known to cause kidney damage. El-Mowafy
said, “DHA elicited prominent chemopreventive effects on its own, and
appreciably augmented those of cisplatin as well." He went further and
indicated that DHA can obliterate certain cisplatin-induced toxicity
and damage to kidney tissue.

DHA is an omega-3 fatty acid that is commonly found in cold-water fish
oil, and some vegetable oils. It is a major component of brain gray
matter and of the retina in most mammalian species and is considered
essential for normal neurological and cellular developments. This
study found that, at the molecular level, DHA acts by reducing white
blood cell accumulation, inflammation, and oxidative stress – all
processes that have been linked with tumor growth.

El-Mowafy and his colleagues have called for greater deployment of
omega-3 in the fight against cancer.

Dave
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